The left has long sought to nationalize government, which means a subordination of the states. In the meantime, liberals aren't blind to the advantages red states enjoy over blue states, in terms of siphoning off blue states' productive citizens and enterprises. Liberals see where many businesses choose to relocate. They appreciate that red states are often more affordable to Americans.
Critical to the nation's ongoing experiments in democracy is the imperative to roll back intrusive -- and often coercive -- national government. Washington is an informal ally of blue states, like Maryland, at the expense of red states, via legislation, court rulings, or executive fiat. What Washington can't annex from states outright, it uses taxpayers' dollars to leverage compliance with federal rules and regulations.
The Obama presidency has been largely an attempt by the left to reenergize and reassert national government at the expense of true federalism. President Obama is the "anti-Reagan." The left wants leftism regnant in every state and locality and is using a bolder national government to impose itself.
But the left's error may be in thinking that conservative Americans will eventually go quietly into the good night, permitting the left to work its will. Big fights loom if the left continues to try to ram its agendas down the throats of red state Americans (ObamaCare is a first critical battle). There's now a long history of leftism in America. The right's rejection of leftism is grounded in the left's demonstrated failures and in cultural and societal constructs that conservative Americans view as wrong-headed and deficient. The lines have been drawn and set.